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Pharmacogenomics

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Drug Effectiveness

Interindividual genetic variations significantly influence individual responses to therapeutic drugs, with over 38% of patients expected to be poor responders to specific medications. This variability can lead to ineffective treatments and missed therapeutic opportunities. Genetic testing allows for the prediction of therapy response, facilitating personalized approaches that improve effectiveness and minimize medication risks for patients.

Adverse Drug Reactions

The conventional 'trial-and-error' and 'one-size-fits-all' approach to medication prescribing often results in increased drug toxicity and treatment failures. Adverse drug reactions rank as the fourth leading cause of death in the United States. Testing for Genetic variations can predict individual patient responses to therapies, enabling physicians to prescribe medications with greater safety and efficacy. At Helix Lab Partners, we offer one of the most clinically actionable pharmacogenomics panels, tailored for specialties such as pain, cardiology, and psychiatry/ADHD among other specialties.

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Pharmacogenomics Provides Crucial Insight To

  • Identify medications that are effective for you.

  • Provide guidance on medication dosing.

  • Reduce the potential for side effects and adverse drug reactions (ADRs).

Who May Benefit from Pharmacogenomic testing?

  • Patients taking medications with pharmacogenomic indications in their package inserts.

  • Patients taking multiple medications.

  • Patients experiencing side effects from their current medications.

  • Patients not experiencing benefits from their current medications.

  • Patients who have experienced adverse drug events while on medications.

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Why Pharmacogenomics?

  • Better therapeutic efficacy.

  • Fewer adverse drug reactions (ADRs).

  • Healthcare cost savings.

  • Overall, improved patient care and increased quality of life for patients.

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References

  1. Spear BB et al. (2011) Clinical Trends in Molecular Medicine. 7 (5): 201-204

  2. http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/DrugInteractionsLabeling/ucm110632.htm

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